Multiplicity Issues in Clinical Trials 2010

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Full-day course taught by Frank Bretz and Alex Dmitrienko at a Société Francaise de Statistique (SFdS) meeting in Paris, France on October 14-15, 2010.

Back to Short Courses.


Dmitrienko A, Tamhane A, Bretz F (editors). Multiple Testing Problems in Pharmaceutical Statistics. Chapman and Hall/CRC, 2009.

SAS programs

Download ZIP archive with R programs for Lectures 2, 7 and 8 in this course.

For more information on software implementation of commonly used multiple testing procedures and gatekeeping procedures, see Implementation of Multiple Testing Procedures and Implementation of Gatekeeping Procedures.


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Dmitrienko, A., Kordzakhia, G., Tamhane, A.C. (2011). Multistage and mixture parallel gatekeeping procedures in clinical trials. Journal of Biopharmaceutical Statistics (in press).

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